Smarter route design. Faster discovery.
SmartChemistry® Retrosynthesis is the next evolution of ICSynth – redesigned from the ground up with a modern interface, expanded data capabilities, and a sharper focus on actionable synthesis planning. Built for chemists, this intuitive software combines advanced AI with curated chemical knowledge to help you quickly explore, compare, and select optimal synthetic routes.
What’s new?
Modern, Intuitive Interface
A completely reimagined user experience designed for speed, clarity, and chemist-friendly navigation.
Expanded Data Sources
Leverage richer datasets from commercial building blocks to in-house libraries and reaction databases – to uncover more realistic, accessible routes.
Smarter Ranking & Filtering
Advanced scoring algorithms help you prioritize routes based on cost, feasibility, step count, novelty, and more.
Seamless Workflow Integration
Built to work with the SmartChemistry® ecosystem, enabling smooth transitions from retrosynthesis to experimental design and optimization.
Key Features:
Ideal for:
▪ Medicinal chemists seeking fast, feasible routes to new targets
▪ Process chemists evaluating scalable synthesis options
▪ Discovery teams exploring route diversity and novelty
▪ CDMOs and CROs delivering faster, cost-effective synthesis planning